Measles Antibody (IgG and IgM) Test Price in Vani Vihar

Test Description

Measles antibody testing detects immune status against measles virus (Rubeola), caused by Morbillivirus — one of the most contagious infectious diseases known with a basic reproduction number (R0) of 12–18. Measles IgM antibodies appear 3–5 days after rash onset, peak at 1–2 weeks, and persist for 1–2 months, indicating acute or recent infection. A positive IgM result confirms acute measles. Measles IgG antibodies develop 2 weeks after natural infection or vaccination and persist for life, conferring protective immunity. Measles IgG (serology) is used to determine immune status in: healthcare workers (must demonstrate immunity), pregnant women, immunocompromised patients, post-exposure prophylaxis assessment, and travelers to endemic areas. Seroconversion (change from IgG-negative to positive) or ≥4-fold rise in IgG titer confirms recent infection in paired acute and convalescent samples. Plaque reduction neutralization test (PRNT) is the gold standard for confirming seronegative status but is performed only in reference laboratories. MMR (measles-mumps-rubella) vaccination is the most effective prevention; herd immunity requires >95% vaccination coverage.