24-Hour Urine Protein Test Price in Bomikhal

Test Description

The 24-hour urine protein test measures the total amount of protein excreted in urine over a complete 24-hour period, providing a more accurate assessment of protein loss than a spot urine protein-to-creatinine ratio. Normal 24-hour urine protein: <150 mg/day. Persistent proteinuria is a key marker of kidney disease: 150–300 mg/day: microalbuminuria (early diabetic nephropathy) — though now standardly measured as albumin-to-creatinine ratio (ACR); 300 mg/day–3.5 g/day: moderate non-nephrotic proteinuria; >3.5 g/day: nephrotic-range proteinuria. Nephrotic syndrome: characterized by heavy proteinuria (>3.5 g/day), hypoalbuminemia (<3.0 g/dL), edema, and hyperlipidemia. Common causes: minimal change disease (children), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (primary or cancer-associated), diabetic nephropathy, and amyloidosis. Protein composition can be assessed by urine protein electrophoresis (UPEP) to distinguish selective proteinuria (predominantly albumin, as in MCD) from non-selective (mixed albumin and globulins, as in FSGS or membranous). Monitoring proteinuria response to therapy (corticosteroids, immunosuppressants) is a key endpoint in glomerulonephritis management.